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KMID : 1159320230250030231
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Korean Journal of Vision Science
2023 Volume.25 No. 3 p.231 ~ p.241
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Analysis of Corneal Endothelial Cells Measured by Noncontact Specular Microscopy in 20s
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Shin Dong-Won
Kim Hyo-Jin
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Abstract
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Purpose : Morphological analysis of corneal endothelial cell was conducted in young adults Korean in their 20s, and differences according both eyes, sex, refractive surgery, contact lenses, COVID-19 infection were investigated.
Methods : A total of 87 (174 eyes) men and women in their 20s were enrolled in a university in Chungcheongnam-do. Morphological analysis of corneal endothelial cell was examined using a noncontact specular microscopey, and corneal endothelial cell density, endothelial cell polymorphism, hexagonal ratio, and central corneal thickness were analyzed. The SPSS 18.0 program was used to compare differences in corneal endothelial cell density, pleomorphism, and hexagonal ratio according to both eyes, sex, and other variables investigated.
Results : The density of corneal endothelial cell was 2,977.7±238.7 cells/mm2 in the right eye and 3,008.9±236.7 cells/mm2 in the left eye (p=0.056). Men had 2,970.9±237.9 cells/mm2 and women had 2,983.6±241.8 cells/mm2, and there was no statistically significant difference (p=0.807). Polymorphism and hexagonal ratio of corneal endothelial cell were also not significantly different according to both eyes, sex, refractive surgery, COVID-19 infection (p>0.050). However, the polymorphism and hexagonal ratio of corneal endothelial cell according to whether or not they wore contact lenses were 30.7±4.5% and 61.9±5.4% in the contact lens wearing group and 28.2±4.0%, and 64.7±4.7% in the control group (p=0.018 and p=0.029, respectively).
Conclusion : The average value of corneal endothelial cell density analyzed in Korean in their 20s was 2,993.3±237.5 cells/mm2, and there was no difference between both eyes and sex.
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KEYWORD
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Central corneal thickness, Corneal endothelial cell density, Corneal endothelial cell polymorphism, Corneal endothelial cell hexagonal ratio, Non-contact specular microscopy
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